Creative Biogene is a genomics and proteomics product and service supplier for university and governmental research organizations, as well as the pharmaceutical and biotechnology industries, based in the United States. It supplies customers in the life science research industry with customized molecular biology reagents and skilled technical services. Enzyme, PCR, vector, transfection reagent, cDNA, and shRNA technologies, as well as transfected stable cell lines, are all part of the company's extensive product portfolio.
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The CRISPR-Cas9 system is adaptable, simple, selective, and low cytotoxic, requiring just one Cas9 endonuclease to complete the reaction.
Microbe genome editing with CRISPR offers a quick turnaround time and a good history in creating CRISPR methods for novel microorganisms.
Genes required for several biological processes are identified by CRISRP knockout screening. It aids in the discovery of new functions for known genes. This screening is effective at identifying possible targets for novel drugs by combining diverse chemicals.
Other than totally knocking out a gene, CRISPRi screening is used to explore its function by downregulating its expression and function. This approach is useful for evaluating the function of genes that cause death when knocked out.