Merck KGaA is a research and technology firm headquartered in Germany that operates in three business segments: healthcare, life sciences, and performance materials. The Healthcare division focuses on creating medications, diagnostic substances, and medical devices in therapeutic areas such as allergies, fertility, oncology, and neurodegenerative diseases, as well as developing drugs, diagnostic substances, and medical devices. The Life Sciences division delivers biotechnology and pharmaceutical research solutions. Laboratory water systems, gene-editing tools, cell lines, and end-to-end drug manufacturing systems are among the products available. Specialty chemicals for a variety of purposes are provided by the Performance Materials division.
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- Merck's genome-editing technology is a game-changer. Researchers will be able to screen single cells utilizing CRISPR libraries employing Feature Barcode technology. These findings could lead to the discovery of new molecular therapeutic targets in immuno-oncology, autoimmune, neurodegeneration, and other human diseases, as well as speed up drug development.
- Single-cell transcriptomics technology provides a ready-to-use tool for measuring gene perturbation and unbiased gene expression in single cells.
- Screening with CRISPR when single-cell transcriptomics is integrated with phenotyping, each phenotype may be isolated and thoroughly profiled using gene expression patterns, resulting in a dynamic perspective of the genes driving phenotype and morphology and a deeper understanding of the underlying biology.
- Merck DNA Preparation & Cloning tools are engineered to achieve certain scientific and technological objectives. The tools speed up research by expressing huge amounts of recombinant protein to establish structural-function linkages, or cloning and expressing a genetically changed gene to investigate its impact on a biological process.